Monday, December 10, 2012

Metal–Organic Transmembrane Nanopores


Department of Chemical and Pharmaceutical Sciences,University of Trieste, via Giorgieri 1, I-34127, Trieste, Italy
J. Am. Chem. Soc., Article ASAP
DOI: 10.1021/ja310425j
Publication Date (Web): November 29, 2012
Copyright © 2012 American Chemical Society

A stable tetraporphyrin metallacycle with Re(I) corners (1) is capable of forming nanopores in a liposomial membrane, provided that the porphyrin units are properly functionalized with peripheral carboxylic acid residues that, by establishing an hydrogen bond network, allow the formation of dimers that span the depth of the membrane.

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